I. mirum! FUSTUS nimia Supplementatione durante graviditate ut impear foetus memoria?
A studio published in MMXVII in Humanum Molecular Geneticorum Munered Antiving ex Academia Community: A Team a McGill University in Canada inventa quod pascens gravida mures a Maximum dose of Saccharum Folic Acidum (XX mg / kg, decies vexillum victu) ducitur ad "Pseudo mthfr defectus" in foliis suis operatio Key enzyme mthfr in iecoris reducitur per ter, unde in methyl metabolism perturbationes, decrescebat embryonic pondus et hippocampal ATROPHIA Et minus firmae brevi-term memoria test ustulo ad tres hebdomades aetatem.
Quid hoc fit?
Traditional Saccharum Folic Acidum (fa) oportet converti a mthfr enzyme in suum activam forma, V, methyltetrahydroperoic Acidum (mthf), utendum corpus. Sed summus dose of synthetica Folic acidum potest "flumen" metabolicae viam, inhibentes actionem de mthfr enzyme. Hoc est a negotiationis jam in via, quae prohibet clavem commeatus ab transferri, ultimately ducens ad penuriam de methyl donatorum (ut s-adenosylmethionine), afficiens DNA methylation et Neurotransmitter synthesis et causing foetus cerebrum progressionem ad "Veer off cursum."
II. In metabolicae captionem synthetica folic Acidum: Magis suppletionem ≠ melius effusio
Sunt "duo cratibus "ad metabolismi synthetica folic acidum in humana corpus:
Enzyme operatio Dependence:78,4% of populus have mthfr gene variationes (ut C677T), in se humilis enzyme operatio faciens eos proni ad metabolicae Morbositates cum suppleatur cum Saccharum folic acidum.
Dose sensibilitatem:Synthetica Folic acidum excess physiologica necessitates potest competitively inhibere in mthfr enzyme et cumulare unmetabolifoled folic acidum in sanguine, augendae Periculum colonia et pectus cancer.
III. Naturalization Foste - Magnafonoeolate Skip In metabolicae crustles, tutum et praecisa Folte suppletionem
Ut naturalised (Active) Foste, Magnafonoeolate (6s-V, Methyltetrahydropteroic acidum) non eget Conversio per mthfr enzyme et directe absorbetur et usus est Corpus, ita avoiding metabolicae foveisque traditum synthetica folic Acidum:
Nulla metabolicae onus:Magnafonoeolate habet puritatem≥99.8% et participat in methyl cursus in "complevit productum forma," sicut directe supplendo "Fuel" ad cellulis, sine freti in mthfr enzyme, faciens illud efficiently utilizable etiam ab hominibus in mthfr gene mutationes.
Donercle dose:Directus Effusio sine periculo accumulanting unmetabolifolized folic acidum.
Solum verificationis:Certified Ut "Naturalization FALTE," non efficaciter non-toxicus, nihil Observatum inhibitionis Mthfr enzyme operatio post terminum usum, nec Embryonic development abnormalities inventa in summus dose coetus a mus experimenta (equivalent ad C temporibus commendatur humana dose).
IV. A scientific dux ad Foste Suppletionem pro expectantia matres
Eligere ius forma: prioritize Active Foste (ut Magnafonoonim), praesertim gravida mulieres cum mthfr Gene Mutationem detections vel familiae historia neural tubum defectus.
Imperium dose: Commendatur quotidie attractio fose in graviditate est 600-800μg. Cautus est consilium cum plus quam CCμG / Dies Saccharum Folic Acidum Ad vitare periculum accumulanting unmetabolifolized folic acidum.
Monitoring dynamic: Regulariter Test Serum Foste et Homocysteine campester ad vitare "Pseudo-normalis" Foste gradus per synthetica folic acidum (excelsum sanguinem foste sed insufficiens intracellular operatio).
V. Conclusio: Get Foste Right A Smarter Infans
Ex Canadian Muris experimenta ad humana orci studiis, magis et magis indicat quod Foste suppletionem non "magis, in melius." Metabolicae ferventia de traditional synthetica folic acid potest conversus suppletionem in "Tempus bomb."
Contra, Magnafonoonim: et proprietates non metabolism opus et excelsum salutem et Efficens, providet meliorem solutio pro prenatal nutritional suppletionem-ensuring quod omnis aliquantulus of flatse verius ad "Campo" de foetus progressionem, cum nihil deserta et non periculum.
Scientific Tip: Si eligens Active Foste, commendatur eligere fontes flatti cum Naturalizantur certification et excelsum castitatem test tradit (ut Magnafonoonam) et sub ductu medico.